Process GO Term cytokinesis and related genes


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Gene NameORF NameFunction GO TermProcess GO TermComponent GO TermInteracting GenesDescriptionGene ProductPhenotype
AXL1YPR122Wmetalloendopeptidase activitybud site selection*integral to membrane*YKL011C YPR111W determinant in axial budding pattern of haploid cells, involved in processing of a-factorhuman insulin-degrading endoprotease homolog (putative)Null mutant is viable; exhibits reduced a-factor expresion; haploid mutants show bipolar budding pat
AXL2YIL140Wmolecular_function unknownbud site selection*bud neck*involved in polarity establishment/cellular polarization during buddingAXL2 can serve as a multicopy suppressor of rho3 and is required for the haploid axial budding patte
AYR1YIL124Wacylglycerone-phosphate reductase activityphosphatidic acid biosynthesiscytoplasm*YLR295C YLR447C YGL137W YBR017C Subcellular location of Ayr1p: lipid particles and endoplasmic reticulum of the yeast1-acyl dihydroxyacetone phosphate reductaseNull mutant is viable. ybr159w/ayr1 double mutant is inviable.
BNI4YNL233Wprotein bindingcytokinesiscontractile ring (sensu Saccharomyces)YPL066W YDR388W YNL271C YJL095W YBL061C YLR337C YJR118C YDR162C YGR229C YNR051C YBR260C YCR009C YLR342W YDL117W YCR002C YBL047C YKL032C YLL021W YML115C YBR234C YDL029W YER133W YGR014W YDL225W YKL079W YHR030C YOR326W bud neck involvedrequired to link Chs3p and Chs4p to the septinsNull mutant is viable, shows delocalized chitin, elongated buds, enlarged bud necks
BNI5YNL166Cmolecular_function unknowncytokinesis*bud neck*YDR136C YDR368W YGR078C YNL153C YML094W bud neck involved; localizes to mother-bud neck in a septin-dependent manner; bni5 shows synthetic eNull: Null mutant is viable, interacts genetically with CDC3, CDC10, CDC11, and CDC12 (septin) genes
BUD13YGL174Wmolecular_function unknownbud site selectionnucleusYGL216W YMR012W YIR005W YLR016C YLR418C YLR085C Null mutant is viable; diploid null mutants exhibit unipolar budding and elongate phenotype.
BUD16YEL029Cmolecular_function unknownbud site selectioncytoplasmNull mutant is viable; random budding in diploid null mutants.
BUD17YNR027Wmolecular_function unknownbud site selectioncellular_component unknownNull mutant is viable; random budding in diploid null mutants.
BUD19YJL188Cmolecular_function unknownbud site selectioncellular_component unknownYMR307W YGR229C Null mutant is viable; random budding in diploid null mutants.
BUD20YLR074Cmolecular_function unknownbud site selectionnucleusYCR072C YJL122W YBL044W YGL068W YFL006W YIR003W YLL050C YMR303C YPR016C YLR196W YPL093W YHR052W YHR179W YDR155C YKL085W YNR053C YJR144W YGL120C YIL070C YNL182C YBL002W YER126C YDL051W YKL009W YNL002C YGR245C YDR101C YER006W YGR103W YHR085W YHR197W YKNull mutant is viable; random budding in diploid null mutants
BUD22YMR014Wmolecular_function unknownbud site selectionnucleusYOR264W Null mutant is viable; random budding in diploid null mutants
BUD23YCR047CS-adenosylmethionine-dependent methyltransferase activitybud site selectioncellular_component unknownYNL282W YLR339C Null mutant is viable; random budding in diploid null mutants
BUD25YER014C-Amolecular_function unknownbud site selectioncellular_component unknownYKL190W YHR181W involved in bipolar buddingNull mutant is viable; random budding in diploid null mutants
BUD26YDR241Wmolecular_function unknownbud site selectioncellular_component unknownNull mutant is viable; random budding in diploid null mutants
BUD27YFL023Wmolecular_function unknownbud site selectioncellular_component unknownYLR243W YLR200W YER133W YCL017C YBR154C YKL113C Function required for yeast viability on toxin exposureNull mutant is viable but exhibits K1 killer toxin hypersensitivity; Diploid null mutants exhibit ra
BUD28YLR062Cmolecular_function unknownbud site selectioncellular_component unknownDiploid null mutants exhibit random budding
BUD3YCL014Wmolecular_function unknowncytokinesis*contractile ring (sensu Saccharomyces)YIL104C YJR092W YBL038W YGR220C YJR091C YPR086W YHR197W cell cycle regulated protein required for axial bud formation; co-assembles with Bud4p at bud sitesNull mutant is viable; bipolar budding pattern in all cell types
BUD30YDL151Cmolecular_function unknownbud site selectioncellular_component unknownYLR103C YDL017W Function required for yeast viability on toxin exposure; random budding in diploid null mutantsK1 killer toxin hypersensitivity
BUD31YCR063Wmolecular_function unknownbud site selectioncellular_component unknownYMR213W YHR165C YDR408C Diploid mutants exhibit random budding
BUD4YJR092WGTP bindingbud site selection*contractile ring (sensu Saccharomyces)YCL014W co-assembles with Bud3p at bud sitesNull mutant is viable, haploids have dipolar budding, normally they have axial budding, no effects o
BUD7YOR299Wmolecular_function unknownbud site selectioncellular_component unknownYGR294W YJR116W YKR070W YLR108C YMR293C YNL308C YOL064C YGL095C YHL007C YDL108W YGR236C YML041C YNL246W YNR069C YOL156W YOR037W YOR047C YOR049C YKL082C YPR054W bud site selectionDiploid-specific heterogenous bud site selection
BUD9YGR041Wmolecular_function unknownbud site selectionbud neckYPL251W YGR041W YDR316W among a group of genes whose products are necessary for bud-site selection; likely involvement in poIn null mutants bipolar-budding cells bud preferentially at distal pole
CYK3YDL117Wmolecular_function unknowncytokinesiscellular_component unknownYER177W YNL271C YER016W YDL225W YNL233W YHR142W YCR009C YDR388W involved in CYtoKinesisNull mutant is viable, exhibits slow growth, mild cytokinesis defects, and aberrant mother-bud neck
EGT2YNL327Wcellulase activitycytokinesiscell wall (sensu Fungi)YLL039C cell-cycle regulation protein, may be involved in the correct timing of cell separation after cytoki
HOF1YMR032Wcytoskeletal protein bindingcytokinesiscontractile ring (sensu Saccharomyces)YDR203W YNL271C YLR423C YBR260C YER144C YGR250C YJL039C YJR090C YNL152W YOR324C YPL059W YIL159W YCR054C YOR098C SH3 domain containing-protein required for cytokinesisNull mutant is defective in cytokinesis
PIK1YNL267W1-phosphatidylinositol 4-kinase activitycytokinesis*nucleus*YDR099W catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokiphosphatidylinositol 4-kinaseNull mutant is inviable; overexpression of PIK1 enhances response to mating pheromone; temperature-s
RAX1YOR301Wmolecular_function unknownbud site selectioncellular_component unknownYGR259C A rax1 mutation converts the budding pattern of an axl1 null mutant from bipolar to axial.
RAX2YLR084Cmolecular_function unknownbud site selectionmembrane*Involved in the maintenance of bipolar patternNull mutant is defective in bipolar pattern
SEC4YFL005WRAB small monomeric GTPase activitycytokinesis*actin cap (sensu Saccharomyces)*YOR326W YPR017C YKL079W YLR166C YER136W YFL038C YKR068C YNL272C Secretory vesicle associated Rab GTPase that binds to Sec15p and is essential for exocytosisras homolog|small GTP binding proteinnull is inviable; conditional mutants show defects in secretion and accumulation of post-Golgi vesic
THP1YOL072Wprotein bindingbud site selection*nuclear pore*YJR091C YLR418C Null mutant is viable and shows transcription-associated hyper-recombination and transcription elong