| Gene Name | ORF Name | Function GO Term | Process GO Term | Component GO Term | Interacting Genes | Description | Gene Product | Phenotype |
| SNF2 | YOR290C | general RNA polymerase II transcription factor activity | chromatin modeling | nucleosome remodeling complex* | YGR252W YDR155C YBL038W YNL016W YBR289W YNL207W YBR081C YOL148C YDR073W YJL176C YOL051W YNL236W YHR041C | involved in the coordinate regulation of phospholipid synthesis | transcriptional regulator | sucrose nonfermenting |
| SNF3 | YDL194W | receptor activity* | signal transduction* | plasma membrane | YPL026C YHR092C YKL038W YHR094C YMR011W YDR345C YDL138W YBR112C | glucose sensor | glucose sensor | Null mutant is viable, defective in high affinity glucose transport, unable to grow on low glucose m |
| SNF4 | YGL115W | protein kinase activator activity | regulation of transcription from Pol II promoter* | nucleus* | YER027C YJL114W YMR291W YGL019W YDR032C YJR083C YDR028C YER177W YDR422C YIL035C YPR160W YDR477W YOR018W YOR267C YER129W YGL208W YML110C YDL214C YKL193C YGL158W YOL139C YGL179C YFR028C YCL046W YLR039C YLR262C YGL027C | involved in release from glucose repression, invertase expression, and sporulation | associates with Snf1p | Null mutant is viable, sucrose nonfermenting; high copy MSI1 and PDE2 partially suppress sporulation |
| SNF5 | YBR289W | general RNA polymerase II transcription factor activity | chromatin modeling | nucleosome remodeling complex* | YFL049W YOL148C YPL016W YKR001C YHL025W YJL176C YOR290C YPL129W YGR252W YMR033W YNR023W YNL207W | Involved in global regulation of transcription | chromatin remodeling Snf/Swi complex subunit | Null mutant is viable, sucrose and raffinose nonfermenter |
| SNF6 | YHL025W | general RNA polymerase II transcription factor activity | chromatin modeling | nucleosome remodeling complex* | YBR289W YML092C YLR438W | Involved in global regulation of transcription | chromatin remodeling Snf/Swi complex subunit | Null mutant is viable, sucrose and raffinose nonfermenter |
| SNF7 | YLR025W | molecular_function unknown | late endosome to vacuole transport | cytoplasm* | YLR025W YDR541C YLR447C YMR154C YOR275C YPR173C YGR122W | Involved in derepression of SUC2 in response to glucose limitation | | Null mutant is viable. Similar to disruption SNF8, SNF7 disruption causes a fewfold decrease in inve |
| SNF8 | YPL002C | molecular_function unknown | protein-vacuolar targeting* | endosome | YDR383C YLR417W YJR102C YPR086W | appears to be functionally related to SNF7 | | Null mutant is viable, sporulation defective, grows poorly on raffinose as a carbon source, shows a |
| SNG1 | YGR197C | molecular_function unknown | response to drug | membrane | | Involved in nitrosoguanidine resistance | | Null mutant is viable, sensitive to various chemical mutagens |
| SNL1 | YIL016W | molecular_function unknown | nuclear pore organization and biogenesis | membrane* | YMR222C | Suppressor of nup116-C lethal. Snl1p is the first Bag domain protein identified in S. cerevisiae. | 18.3 kDa integral membrane protein | Null mutant is viable; SNL1 is a high copy suppressor of nup116, gle2 and nic96 alleles |
| SNM1 | YDR478W | ribonuclease MRP activity | rRNA processing | ribonuclease MRP complex | YDR318W YNL221C | Has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. | | Null mutant is inviable |
| SNP1 | YIL061C | mRNA binding | nuclear mRNA splicing, via spliceosome | snRNP U1* | YCR101C YFR039C YGR203W YMR009W YDL047W YLR386W YAR018C YBR034C YBR247C YPR191W YIL070C YMR319C YBL045C YDR240C YGR013W YMR125W YMR290C YHR044C YAL047C YIL033C YML074C YOR275C YJL098W YKR028W YBL022C YML046W YKL012W YDR235W YHR165C YBR117C YPL178W YD | U1snRNP 70K protein homolog | U1snRNP 70K protein homolog | Null mutant is inviable in some strain backgrounds and in other strain backgrounds, null mutant is v |
| SNQ2 | YDR011W | xenobiotic-transporting ATPase activity | response to drug* | plasma membrane | | ABC transporter | ABC transporter | null mutant is viable; overexpression confers multi-drug resistance |
| SNT1 | YCR033W | NAD-dependent histone deacetylase activity* | histone deacetylation* | histone deacetylase complex | YGR172C YDR155C YMR273C YBR103W YJL168C YLR200W YGR078C YAL013W | | | |
| SNT309 | YPR101W | molecular_function unknown | nuclear mRNA splicing, via spliceosome | spliceosome complex | YMR213W YLR117C YPR182W YKL095W YNL201C YLL036C | Synergistic to prp19 (NineTeen) mutation. Essential for mRNA splicing. | protein complex component associated with the splicing factor Prp19p | Null mutant is viable, temperature sensitive, exhibits defects in splicing at elevated temperature; |
| SNU114 | YKL173W | pre-mRNA splicing factor activity* | nuclear mRNA splicing, via spliceosome | snRNP U5* | YMR213W YLR117C YDR283C YER146W YNL147W YDL087C YHR086W YDL208W YGR091W YPR178W YGL120C YAL032C YGR074W YFL017W-A YPR182W YBR152W YKL095W YIR009W YHR165C YBL050W | involved in splicing | U5 snRNP-specific protein related to EF-2 | Null mutant is inviable; growth inhibitory when over-expressed; required for pre-mRNA splicing in vi |
| SNU13 | YEL026W | pre-mRNA splicing factor activity | nuclear mRNA splicing, via spliceosome* | nucleolus* | YDR060W YMR059W YDL138W | part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); RNA binding protein (puta | U3 snoRNP protein|U4/U6.U5 snRNP component | the null mutant is inviable |
| SNU23 | YDL098C | pre-mRNA splicing factor activity | nuclear mRNA splicing, via spliceosome | small nuclear ribonucleoprotein complex | YGR075C YNL147W YPR178W YBR152W YDR318W | 23 kD U4/U6.U5 snRNP associated protein | RNA binding zinc finger protein (putative) | the null mutant is inviable |
| SNU56 | YDR240C | mRNA binding | nuclear mRNA splicing, via spliceosome | snRNP U1* | YPL178W YDL087C YBR119W YHR086W YGR074W YFL017W-A YIL061C YLR298C | Snurp = Small nuclear ribonucleoprotein particle of MW 56 kDa. Associated with the U1 snRNP; no coun | U1 snRNP protein | Null mutant is inviable; mutation affects the in vitro formation of commitment complexes and spliceo |
| SNU66 | YOR308C | pre-mRNA splicing factor activity | nuclear mRNA splicing, via spliceosome | small nuclear ribonucleoprotein complex | YLR147C YPR178W YDR283C YNL147W YDL208W YGR091W YHR165C YFL017W-A YBR152W YDR268W YML016C YBR198C YBR195C YLR418C YLR085C YMR263W | 66kD U4/U6.U5 snRNP associated protein | | |
| SNU71 | YGR013W | RNA binding | nuclear mRNA splicing, via spliceosome | snRNP U1* | YIL009W YKL012W YPL178W YDL087C YBR119W YHR086W YFL017W-A YPR182W YIL061C YMR125W YDR080W YLR298C | associated with U1 snRNP (no counterpart in mammalian U1 snRNP; contains few SR-, RE- and RD-dipepti | U1 snRNP protein | Null mutant is inviable |
| SNX4 | YJL036W | lipid binding | transport* | membrane | YLR423C YDR425W YDL113C YBR274W YLR262C YDR126W | Sorting NeXin | | Defective in maturation of the vacuolar protein, aminopeptidase I |
| SNX41 | YDR425W | protein transporter activity | protein transport | endosome | YJR110W YGR172C YJL036W YGL161C YGL198W YKR014C YPL280W | sorting nexins Snx4p, Snx41p, and Snx42p mediate distinct retrieval pathways from endosomes. | | |
| SOD1 | YJR104C | copper, zinc superoxide dismutase activity | zinc ion homeostasis* | cytosol* | YLR369W YHR135C YKL095W YNL135C YMR059W YDL101C YBR055C YBR109C YPL031C YGL018C YCL017C YMR190C YKL113C YPR141C YPR135W YLR103C YER173W YHR154W | Cu, Zn superoxide dismutase | Cu, Zn superoxide dismutase | Null mutant is viable; dioxygen and paraquat sensitive; fails to grow on lactate as a carbon source; |
| SOD2 | YHR008C | manganese superoxide dismutase activity | oxygen and reactive oxygen species metabolism | mitochondrion* | YBR061C YFR015C YMR106C YML095C YHR031C | Manganese-containing superoxide dismutase | Mn-containing superoxide dismutase | Null mutant is viable; growth is impaired by oxygen; SOD2 is required for sporulation |
| SOF1 | YLL011W | snoRNA binding | rRNA modification* | small nucleolar ribonucleoprotein complex* | YJR064W YNL132W YJL014W YIL142W YDR212W YDR188W YMR229C YBR247C YCL059C YCR057C | part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); 56 kDa nucleolar snRNP pr | U3 snoRNP protein | Null mutant is inviable. sof1-56, a dominant suppressor of nop1 mutants can restore growth and pre-R |
| SOK1 | YDR006C | molecular_function unknown | cAMP-mediated signaling | nucleus | YKL093W YOR178C YER177W | gene dosage suppressors of the conditional growth defect of several temperature-sensitive A kinase m | | Null mutant is viable |
| SOM1 | YEL059C-A | molecular_function unknown | proteolysis and peptidolysis | mitochondrial inner membrane* | | high copy suppressor of imp1 mutation, may be required for the function of the Imp1 peptidase and/or | | Null mutant is viable; proteolytic processing is prevented or reduced |
| SOP4 | YJL192C | molecular_function unknown | ER to Golgi transport | endoplasmic reticulum* | YJR091C | suppressor of pma1-7 | | |
| SOY1 | YBR194W | molecular_function unknown | biological_process unknown | cytoplasm | YPR152C YLR418C YJL030W YBR094W YLR113W | Synthetic with Old Yellow Enzyme | | |
| SPA2 | YLL021W | cytoskeletal regulatory protein binding | establishment of cell polarity (sensu Saccharomyces)* | bud neck* | YLR362W YDL159W YER149C YMR308C YLR319C YOR231W YPL140C YLR147C YHR158C YAL040C YNL293W YOL112W YNL298W YLR229C YNL233W YLR342W YGR229C | | | impaired ability to form schmoos, do not mate well with other spa2 mutants |