| Gene Name | ORF Name | Function GO Term | Process GO Term | Component GO Term | Interacting Genes | Description | Gene Product | Phenotype |
| NTC20 | YBR188C | pre-mRNA splicing factor activity | nuclear mRNA splicing, via spliceosome | spliceosome complex | YDR416W YGL070C YIL034C YLR117C | Prp19p (NineTeen)-associated Complex protein | splicing factor | Null mutant is viable. ntc20 ntc30 double mutant is very sick and accumulates pre-mRNA. Null mutant |
| NTF2 | YER009W | RAN protein binding | protein-nucleus import* | nuclear membrane | YER004W YDL202W YMR059W | May coordinate the Ran-dependent (GSP1/GSP2) association and disassociation reactions of nuclear imp | nuclear transport factor|similar to mammalian cytosolic nuclear import factor NTF2 | Null mutant is inviable; temperature-sensitive mutants are defective in localization of nuclear prot |
| NTG1 | YAL015C | pyrimidine-specific oxidized base lesion DNA N-glycosylase activity* | DNA repair* | nucleus* | YDL029W YMR058W YEL060C YDR214W YMR012W YEL030W YJR068W YNL037C YPR110C YMR146C YDL059C | endonuclase III like glycosylase involved in DNA repair | DNA glycosylase | Null mutant is viable but is sensitive to H202 and menadione |
| NTG2 | YOL043C | pyrimidine-specific oxidized base lesion DNA N-glycosylase activity | base-excision repair, AP site formation | nucleus | YOR264W YCL032W | Endonuclease III-like glycosylase | endonuclease III DNA base excision repair N-glycosylase | |
| NUC1 | YJL208C | endodeoxyribonuclease activity* | DNA recombination* | mitochondrial inner membrane | YKL222C YKR079C YDL130W YNL192W YLR342W | mitochondrial nuclease | nuclease | Null mutant is viable |
| NUD1 | YOR373W | structural constituent of cytoskeleton | microtubule nucleation | spindle pole body | Spindle pole body protein | Null mutant is inviable | ||
| NUF2 | YOL069W | structural constituent of cytoskeleton | chromosome segregation* | condensed nuclear chromosome kinetochore* | YNL086W YMR294W YLR229C YEL034W YIL144W YGR119C YGR238C YER099C | Protein associated with spindle pole body and critical for nuclear division | 53 kDa coiled-coil protein | Null mutant is inviable; temperature-sensitive mutants arrest with single undivided or partially div |
| NUG1 | YER006W | molecular_function unknown | rRNA processing | nucleus* | YCR072C YPL146C YPL211W YPL093W YHR052W YKL009W YNL002C YGR245C YDR101C YGR103W YHR197W YLR106C YMR290C YNL061W YOR206W YLR002C YDL031W YMR049C YCL054W YER126C YNL284C YGR220C YPL043W YFR031C-A YKR081C YNL110C YPL204W YLR074C YGL081W YDR386W YDL060W | NUclear GTPase | Nuclear GTPase involved in Ribosome biogenesis | Null: dead. |
| NUM1 | YDR150W | tubulin binding | nuclear migration (sensu Saccharomyces)* | bud tip* | YGL217C YLR217W YOR322C YPL205C YNL271C YLR319C YCR077C YLR200W YNL153C YEL003W YJL154C YPL269W YCR065W YEL061C YER016W YGL124C YGL216W YGR078C YGR229C YLR210W YML094W YOR349W YPR141C YGL086W YLR216C YKL007W YIL034C YNL079C YFR019W YMR055C YOR058C YJ | May function in nuclear migration during mitosis and meiosis by affecting astral microtubule functio | contains variable number of tandem repeats of a 64 amino-acid polypeptide, potential Ca2+-binding si | Null mutant is viable; num1-disrupted strains contain many budded cells with two nuclei in mother ce |
| NUP1 | YOR098C | protein binding* | mRNA-nucleus export* | nuclear pore | YDR132C YKL061W YKR064W YOL070C YPR172W YNL189W YHR129C YCR086W YMR159C YOR326W YMR032W YOR370C YGL037C YBR126C YBL058W YAL055W YOR229W YDR395W YKL020C YLL001W YPR187W YMR271C YLR359W YHR068W YMR096W YJR159W YBL079W YDL029W YMR235C YGL016W YBR017C YL | nuclear pore complex protein | nuclear pore complex subunit | Davis and Fink (Cell 61:965-978) report that a NUP1 deletion is inviable, whereas Schlaich and Hurt |
| NUP100 | YKL068W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YBR216C YDR034C YDR335W YGR218W YNL243W YDL207W YMR047C YER107C YLR347C YNL298W | Participates in nucleocytoplasmic transport; member of GLFG-containing family of nucleoporins | nuclear pore complex subunit | Null mutant is viable with no obvious phenotypes; synthetically lethal with nup116 and gle2 mutants |
| NUP116 | YMR047C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YAR066W YBL094C YBR027C YBR137W YBR144C YBR273C YDR271C YGR139W YGR151C YHL049C YHR209W YIL055C YJL061W YJR079W YJR136C YJR141W YKL061W YKL088W YLR077W YLR294C YLR312C YLR434C YMR157C YMR206W YNL194C YNL300W YNL319W YNR040W YNR061C YNR074C YOL111C YO | Involved in nucleocytoplasmic transport; may be required for biogenesis of tRNA | nuclear pore complex subunit | Null mutant grows slowly, accumulates unspliced pre-tRNAs, acumulates poly(A)+ RNA in the nucleus, a |
| NUP120 | YKL057C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YGR161C-C YOR142W-A YER086W YNR012W YGL092W YGR249W YLR208W YDL116W YAL009W YHR004C YLR216C | Nucleoporin | 100 kDa protein (predicted molecular weight is 120 kDa) with two leucine zipper motifs, coiled-coil | Null mutant is viable but grows slower, is temperature-sensitive, and shows nucleolar fragmentation |
| NUP133 | YKR082W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YDL116W YLR208W YLR330W YJL099W YHR142W YJR075W | Nuclear pore complex protein involved in poly(A)+ RNA transport, nuclear pore distribution, and poss | nuclear pore complex subunit | Null mutant is viable but grows slowly and is temperature-sensitive; at nonpermissive temperature, p |
| NUP145 | YGL092W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YER107C YGL060W YLR208W YGR178C YHR036W YKL057C YMR153W YPR111W YGL100W YDL116W YLR347C | Nuclear pore complex protein with GLFG motif | nuclear pore complex subunit | Null mutant is inviable, depletion of Nup145p in vivo leads rapidly to nuclear retention of polyaden |
| NUP157 | YER105C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YIL061C YJL030W YMR153W YEL015W YBL079W YJL061W YPR120C | yeast nuclear pore complex component | nuclear pore complex subunit | Null mutant is viable; synthetically lethal with nup170 and nup188 |
| NUP159 | YIL115C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YDR395W YDL207W YJL041W YJL061W YLR347C YOR160W YJR132W | Located on cytoplasmic side of nuclear pore complex; may be involved in nuclear import or mRNA expor | contains coiled-coil domain and repeated motifs typical of nucleoporins|nuclear pore complex subunit | Null mutant is inviable; at nonpermissive temperature, a temperature-sensitive mutant shows cessatio |
| NUP170 | YBL079W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YOR098C YER105C YJL061W YLR335W | Component of yeast nuclear pore complex; may play a role in localizing specific nucleoporins to nucl | nuclear pore complex subunit | Null mutant is viable; synthetically lethal with nup157, nup188, and pom152; changing NUP170 express |
| NUP188 | YML103C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YMR129W YAL009W YFR002W | Localized at both the cytoplasmic and nucleoplasmic faces of the nuclear pore complex (NPC); may for | nuclear pore complex subunit | Null mutant is viable but exhibits abnormalities in nuclear envelope and nuclear pore morphology; do |
| NUP192 | YJL039C | structural constituent of nuclear pore | nuclear pore organization and biogenesis | nuclear pore | YBR059C YMR153W YMR032W YBR270C YLR447C YFR002W | large yeast nucleoporin | nuclear pore complex subunit | Null mutant is inviable. |
| NUP2 | YLR335W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YOR020C YGL044C YBL079W YGL016W YNL189W YLR347C YJR132W | Localizes to discrete spots in the nuclear envelope; probably functions in transport through nuclear | nucleoporin | Null mutant is viable; some combinations of alleles of nup1, nsp1 and nup2 are synthetically lethal |
| NUP42 | YDR192C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YOR134W YDL207W YER081W YGR218W YJR069C YNL092W YMR255W YER107C YBR017C | interacts specifically with the HIV-1 Rev protein effector domain; Ulp1 Interacting Protein 1 | 42 kDa protein associated with nuclear pore complexes; structurally related to the FG-nucleoporin fa | Null mutant is viable, NUP42 is essential for the export of heat shock mRNAs following stress |
| NUP49 | YGL172W | structural molecule activity | mRNA-nucleus export* | nuclear pore* | YHR216W YMR294W YNL041C YNL086W YFR002W YJL041W YBR017C YAL034W-A YGR119C | localizes to discrete spots in the nuclear envelope | nuclear pore complex subunit | Null mutant is inviable; some nsp1 nsp49 alleles exhibit synthetic lethality |
| NUP53 | YMR153W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YLR324W YMR153W YGL170C YGL092W YOL129W YER118C YDL088C YDR307W YER026C YGL044C YGL104C YGL237C YHL004W YHR190W YJL039C YJL057C YJL117W YLR295C YML125C YMR298W YNL234W YOL018C YML064C YML031W YFR002W YER105C YMR129W YOL065C | Component of karyopherin docking complex of the nuclear pore complex | karyopherin docking complex component of the nuclear pore complex|nuclear pore complex subunit | Null mutant is viable but disrupts Kap121 localization to the nuclear envelope. |
| NUP57 | YGR119C | structural molecule activity | mRNA-nucleus export* | nuclear pore | YEL043W YKL061W YKL103C YLR423C YMR294W YGR120C YPR046W YDL065C YDR416W YGL172W YGL170C YJL041W YBR017C YMR139W YPR083W YMR236W YGL005C YGR218W YOL069W YOR035C YFR002W YMR308C | Forms complex with Nsp1p, Nup49p, and Nic96p at nuclear pore; this complex participates in nucleocyt | nuclear pore protein (nucleoporin) | Null mutant is inviable |
| NUP60 | YAR002W | structural constituent of nuclear pore | nucleocytoplasmic transport* | nuclear pore | YLR347C YLR418C YPR141C YPR135W YMR078C YCL016C YCL061C YNL273W YNL250W YDR363W | nuclear pore protein | nuclear pore complex subunit | |
| NUP82 | YJL061W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YKL061W YLR423C YER105C YJL041W YIL115C YMR047C YEL005C YFR008W YBL079W | Interacts with nuclear pore complex and participates in nucleocytoplasmic transport; required for po | 82 kDa protein, with putative coiled-coil domain, has carboxy-terminal domain, containing heptad rep | Null mutant is inviable; cells depleted of Nup82p, or cells with temperature-sensitive Nup82p at non |
| NUP84 | YDL116W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YCL044C YCL069W YHR033W YOL014W YPL124W YJL117W YGL179C YKL057C YGL092W YDR113C YHR004C YMR047C YJL041W YOR180C YHL004W YCL051W YCR039C YDL044C YGL263W YJL090C YOR294W YPL091W YLR208W YKR082W YOL131W YJR042W YGL100W YAL009W | component of nuclear pores; Part of complex with Nup120p, Nup85p, Sec13p, and a Sec13p homolog | nuclear pore complex subunit|similar to mammalian Nup107p | Null mutant is viable but has defects in nuclear membrane and nuclear pore complex organization and |
| NUP85 | YJR042W | structural molecule activity | mRNA-nucleus export* | nuclear pore | YMR209C YOR176W YGL100W YPL215W YOR160W YDL116W YPL169C YLR208W YHR004C | Protein in nuclear pore complex; may function in nuclear envelope integrity; may also be involved in | nuclear pore complex subunit | Null mutant is viable but is temperature-sensitive; at nonpermissive temperature, null mutant accumu |
| NUT1 | YGL151W | molecular_function unknown | regulation of transcription from Pol II promoter | nucleus | YPR168W YDL005C YOL135C YBL093C YBR253W YNL025C YDL017W YML094W YLR103C | Negative regulator of URS2 of the HO promoter | Null mutant is viable, deletion of NUT1 causes a constitutive, Swi4p-independent phenotype in combin |